Takayuki Nagai Selected Research

Vaccines

1/2017	Syntheses and mucosal adjuvant activity of simplified oleanolic acid saponins possessing cinnamoyl ester.
6/2010	Oral adjuvant activity for nasal influenza vaccines caused by combination of two trihydroxy fatty acid stereoisomers from the tuber of Pinellia ternata.
3/2003	Total synthesis and adjuvant activity of all stereoisomers of pinellic acid.
7/2002	Pinellic acid from the tuber of Pinellia ternata Breitenbach as an effective oral adjuvant for nasal influenza vaccine.

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Takayuki Nagai Research Topics

Disease

11	Infections 10/2019 - 01/2009
8	Inflammation (Inflammations) 03/2021 - 04/2004
7	Atrial Fibrillation 01/2023 - 12/2007
5	Pneumonia (Pneumonitis) 10/2023 - 10/2018
5	Human Influenza (Influenza) 01/2017 - 07/2002
5	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 12/2015 - 12/2007
4	Neoplasms (Cancer) 01/2023 - 12/2003
4	Choroidal Neovascularization 09/2012 - 12/2007
3	Hemorrhage 03/2021 - 12/2003
3	Tuberculosis (Tuberculoses) 10/2018 - 06/2006
3	Polypoidal Choroidal Vasculopathy 03/2017 - 01/2014
3	Thrombosis (Thrombus) 08/2015 - 08/2006
3	Macular Degeneration (Age-Related Maculopathy) 01/2015 - 04/2009
2	Tachycardia (Tachyarrhythmias) 10/2023 - 01/2020
2	Ventricular Fibrillation 10/2023 - 01/2007
2	Cardiac Arrhythmias (Arrythmia) 10/2023 - 05/2006
2	Cardiovascular Diseases (Cardiovascular Disease) 07/2022 - 12/2007
2	Neuroinflammatory Diseases 01/2022 - 01/2017
2	Critical Illness (Critically Ill) 08/2021 - 01/2021
2	COVID-19 08/2021 - 01/2021
2	Heart Failure 12/2020 - 09/2012
2	Pulmonary Tuberculosis 01/2019 - 05/2013
2	Colorectal Neoplasms (Colorectal Cancer) 10/2018 - 10/2014
2	Sarcoidosis (Schaumann Disease) 01/2016 - 10/2014
2	Ventricular Tachycardia 12/2015 - 05/2006
2	Osteoporosis 06/2013 - 01/2010
2	Retinal Perforations 09/2012 - 10/2011
2	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2012 - 08/2009
2	Asthma (Bronchial Asthma) 01/2011 - 10/2004
2	Myocardial Infarction 08/2006 - 02/2003
1	Atrial Premature Complexes (Premature Atrial Contraction) 01/2023
1	Death (Near-Death Experience) 07/2022
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2022
1	Scotoma (Scintillating Scotoma) 09/2021
1	Ulcer 03/2021
1	Clinical Deterioration 01/2021

Drug/Important Bio-Agent (IBA)

5	Immunoglobulin G (IgG)IBA 01/2021 - 07/2002
4	C-Reactive ProteinIBA 08/2021 - 02/2003
4	VaccinesIBA 01/2017 - 07/2002
3	Poly I-CIBA 10/2023 - 03/2021
3	Oxygen (Dioxygen)IBA 08/2021 - 12/2020
3	CytokinesIBA 03/2021 - 06/2012
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 02/2003
3	Immunoglobulin A (IgA)IBA 10/2019 - 07/2002
3	Ranibizumab (Lucentis)FDA Link 01/2015 - 09/2012
3	Retinaldehyde (Retinal)IBA 06/2014 - 01/2008
3	Diphosphonates (Bisphosphonates)IBA 06/2013 - 12/2007
3	sho-seiryu-toIBA 01/2011 - 07/2002
2	nobiletinIBA 10/2023 - 01/2022
2	Adenosine Triphosphate (ATP)IBA 10/2023 - 01/2020
2	koso-sanIBA 01/2022 - 01/2017
2	cimigenosideIBA 01/2022 - 03/2021
2	MucinsIBA 01/2018 - 06/2015
2	AntibodiesIBA 01/2014 - 12/2011
2	Matrix Metalloproteinases (MMPs)IBA 06/2012 - 08/2006
2	Antiviral Agents (Antivirals)IBA 01/2012 - 07/2002
2	OvalbuminIBA 01/2011 - 10/2004
2	Immunoglobulin E (IgE)IBA 01/2011 - 04/2004
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 05/2010 - 12/2007
2	Therapeutic UsesIBA 01/2010 - 04/2009
2	pinellic acidIBA 03/2003 - 07/2002
1	7,3'-dihydroxy-4'-methoxyisoflavoneIBA 10/2023
1	Brain Natriuretic Peptide (Natrecor)FDA Link 07/2022
1	ligustilideIBA 01/2022
1	hachimijiogan (TJ 7)IBA 01/2022
1	ferulic acid (sodium ferulate)IBA 01/2022
1	HesperidinIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	atractylenolide IIBA 01/2022
1	Viral RNAIBA 01/2022
1	atractylenolide IIIIBA 01/2022
1	bu-zhong-yi-qi-tangIBA 01/2022
1	isoliquiritigenin (GU 17)IBA 01/2022
1	formononetinIBA 01/2022
1	P-SelectinIBA 03/2021
1	TriterpenesIBA 03/2021
1	GlycosidesIBA 03/2021
1	ChemokinesIBA 03/2021
1	tocilizumab (atlizumab)FDA Link 01/2021
1	Serum AlbuminIBA 01/2021

Therapy/Procedure

8	Therapeutics 03/2017 - 05/2006
7	Kampo Medicine (Kampo) 01/2022 - 07/2002
6	Catheter Ablation 01/2023 - 05/2006
4	Oral Administration 03/2021 - 07/2002
4	Drug Therapy (Chemotherapy) 10/2018 - 06/2006
3	Vitrectomy 09/2021 - 01/2008
2	Electric Countershock (Cardioversion) 10/2023 - 08/2015
2	Ligation 03/2021 - 06/2012
2	Photochemotherapy (Photodynamic Therapy) 03/2017 - 01/2014
2	Intranasal Administration 01/2017 - 07/2002
2	Defibrillators (Defibrillator) 01/2016 - 06/2009
2	Cardiac Resynchronization Therapy 01/2016 - 09/2012
2	Lasers (Laser) 04/2009 - 12/2007
1	Heterologous Transplantation (Xenotransplantation) 01/2023
1	Precision Medicine 01/2023
1	Patient Readmission 07/2022
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2022
1	Renal Dialysis (Hemodialysis) 08/2021
1	Surgical Instruments (Clip) 03/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2021